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US surgeons transplant pig kidney into living human — first time ever

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Surgeons at Massachusetts General Hospital in the United States have transplanted a pig’s kidney into a living human recipient for the first time.

In a statement announcing the “major milestone”, the hospital said a genetically edited pig kidney was used, while the surgery took four hours.

The surgeons called the transplant a “success” and said the patient is recovering well and is expected to be discharged on Saturday.

The patient, 62-year-old Richard Slayman, has been living with type 2 diabetes and hypertension for many years.

He was on dialysis for many years before receiving a kidney transplant from a deceased human donor in December 2018 from the hospital.

The kidney began to fail about five years later and Slayman was forced to resume dialysis in May 2023.

The hospital said the kidney was provided by eGenesis, a pharmaceutical company, based in Cambridge, from a pig donor genetically-edited using CRISPR-Cas9 technology.

The harmful pig genes were removed while certain human genes were added to improve their compatibility.

The scientists also inactivated retroviruses found in pigs to reduce the risk of infection in humans.

Tatsuo Kawai, a member of the surgical team, attributed the success of the transplant to the efforts of thousands of scientists and physicians over several decades.

“We are privileged to have played a significant role in this milestone. Our hope is that this transplant approach will offer a lifeline to millions of patients worldwide who are suffering from kidney failure,” Kawai said.

This is not the first time an animal organ has been transplanted into a human patient.

In 2023, researchers at NYU Langone Health in New York City transplanted a genetically engineered pig kidney into a 58-year-old man who had been declared brain dead.

Also in 2022 and 2023, the University of Maryland transplanted two genetically-modified pig hearts into terminally ill patients.

But both patients, David Bennett, and Lawrence Facuette, ended up passing away, the first due to heart failure and the second due to organ rejection.

Education

Canada now permits international students to work 24 hours

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Canada has increased the permissible work hours for eligible international students during academic terms from 20 to 24 hours per week.

This adjustment aims to provide greater opportunities for students to gain work experience while maintaining their focus on academics.

Marc Miller, Canada’s Immigration, Refugees, and Citizenship Minister, stressed the intent behind this policy change, saying, “This change will give students more flexibility to manage their time and gain practical experience.”

The decision builds on remarks Miller made in October 2022 when he emphasized the importance of work experience for international students.

At the time, he stated: “With the economy growing at a faster rate than employers can hire new workers, Canada needs to look at every option so that we have the skills and workforce needed to fuel our growth.

“Immigration will be crucial to addressing our labour shortage. By allowing international students to work more while they study, we can help ease pressing needs in many sectors across the country, while providing more opportunities for international students to gain valuable Canadian work experience and continue contributing to our short-term recovery and long-term prosperity.”

Key Changes to the International Student Program
Full-Time Work During Academic Breaks

International students can now work full-time during designated academic breaks, such as summer and winter holidays. These periods allow students to increase their earnings without interfering with class schedules, bolstering their financial stability while continuing their education.

The updated regulations permit students to work up to 24 hours per week during academic terms. This increase offers greater employment opportunities while ensuring students can maintain a sustainable study schedule.

Enhanced Reporting by Institutions

Designated Educational Institutions (DLIs) are now required to submit reports twice yearly to Immigration, Refugees, and Citizenship Canada (IRCC). These reports will confirm students’ enrollment status and academic progress, ensuring compliance with study permit requirements and upholding the integrity of the International Student Program.

Approval for Institution Transfers

Under the new rules, international students must obtain approval before transferring to a different DLI. This requirement ensures adherence to permit conditions and maintains academic standards across Canada’s institutions.

Special Provisions for Quebec Students

In Quebec, eligible international students can work off-campus without a separate work permit, provided they meet specific criteria. Students must be enrolled full-time in post-secondary, vocational, or professional training programs, or vocational training at the secondary level. These courses must be at least six months long and lead to a recognized degree, diploma, or certificate.

By introducing these measures, Canada aims to enhance opportunities for international students while addressing labour shortages in key sectors, ensuring a balance between work experience and academic success.

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Trump appoints Elon Musk to lead department of government efficiency

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US President-Elect Donald Trump has appointed Elon Musk, chief executive officer (CEO) of Tesla and SpaceX, to lead a soon-to-be-established Department of Government Efficiency (DOGE).

Musk, owner of X, the microblogging platform previously known as Twitter, was an avid supporter of Trump during the electioneering leading up to the November 5 presidential election.

The former president defeated Vice-President Kamala Harris after securing more than 270 of the electoral college votes required to win the poll.

A statement on Tuesday said Musk would run DOGE alongside Vivek Ramaswamy, a politician and entrepreneur.

It said the duo “will pave the way for my Administration to dismantle Government Bureaucracy, slash excess regulations, cut wasteful expenditures, and restructure Federal Agencies Essential to the ‘Save America’ Movement’.

“I look forward to Elon and Vivek making changes to the Federal Bureaucracy with an eye on efficiency and, at the same time, making life better for all Americans,” the statement quoted the president-elect as saying.

“Importantly, we will drive out the massive waste and fraud which exists throughout our annual $6.5 Trillion Dollars of Government Spending.”

Trump will take office for a second and final term on January 25, 2025.

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French newspapers sue X for using content without paying

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Major French news organisations say they are suing X, a micro-blogging platform, for allegedly using their content without paying.

According to Reuters, the newspapers, which are Le Monde, Le Figaro and Le Parisien, announced in a statement on Tuesday.

The media platforms said they were due payment under their ancillary rights, which allow payment to news outlets by digital platforms, for the distribution of their content.

They said X, formerly known as Twitter, and owned by billionaire Elon Musk, has never agreed to open negotiations with French news publishers, unlike Alphabet Inc, Google and Meta Platforms Inc.

The publication also said the media organisations claimed that X has not complied with an order issued by the Paris Court of Justice in May to release information required to calculate the amount owed.

“The revenue from these rights, with the investment that it would enable its beneficiaries to make, is a boost to the plurality, independence and quality of the media, which are essential for freedom of expression and the right to information in our democratic society,” the newspapers said.

A spokesperson for the Paris tribunal also confirmed the case to Reuters and said a hearing has been scheduled for May 15, 2025.

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