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66-year-old man becomes oldest patient ‘cured of HIV’ after stem cell transplant

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A 66-year-old man, who prefers to remain anonymous, has reportedly been cured of HIV after undergoing a stem cell transplant.

According to a statement by the City of Hope medical center, US, where the procedure took place, the man has been in remission from the virus for over 17 months after stopping antiretroviral therapy (ART) for the disease.

The centre said he is the fourth in the world and the oldest to go into long-term remission of HIV after receiving stem cells from a donor with a rare genetic mutation.

The patient, who was diagnosed with HIV in 1988, was said to have developed acute myelogenous leukemia in 2018, a cancer of the blood and bone marrow. To treat both the cancer and HIV, doctors performed a blood stem cell transplant with cells from a donor who carried a rare genetic mutation that makes people resistant to most strains of HIV infection — the homozygous CCR5 delta 32 mutation.

“CCR5 is a receptor on CD4+ immune cells, and HIV uses that receptor to enter and attack the immune system. But the CCR5 mutation blocks that pathway, which stops HIV from replicating,’ the statement reads.

“The patient received three different therapies to get him into remission before receiving the transplant. Most patients achieve remission after one therapy. The remission is necessary because a transplant is an intensive procedure that can cause serious complications. The patient did not experience serious medical issues after transplant.

“Since recovering from his transplant, the City of Hope patient has not shown any evidence of having replicating HIV virus in his body, either in blood or tissue samples. With institutional review board approval, he stopped taking ART for HIV in March 2021 and was monitored closely for rebound virus. He might have been able to stop the therapies sooner, but wanted to wait until he was vaccinated against COVID-19. City of Hope is continuing to monitor the patient on an ongoing basis.”

Reacting, the patient said when he was diagnosed with HIV in 1988, he thought it was a death sentence.

“I never thought I would live to see the day that I no longer have HIV. City of Hope made that possible, and I am beyond grateful,” he said.

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5 unexpected side effects of drinking hot water frequently

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Do you know drinking hot water too frequently has several side effects?

It’s of popular knowledge that drinking hot water has a long list of benefits, however frequent intake has several side effects.

Most people think drinking hot water is one of the best ways to stay healthy. This is totally untrue.

Some people drink hot water frequently for several reasons like the weather of a place or health conditions, but it can be harmful to your health. It’s more advisable to take warm water over a hot one.

This article will show you some of the side effects of drinking hot water too frequently.

Most people think hot water is very pure but it’s not completely true. If you’re taking your hot water from the tap, there’s a higher possibility that it has been contaminated.

This is because hot water dissolves contaminants than cold water. If the pipes are too old and rusty, lead particles are likely to mix with the water that flows through the pipes.

It’s advisable to use a kettle to boil your water for safety.

Studies have proven that 55-65% of the body system contains water. Drinking water is healthy as it hydrates the body and flushes out some toxins in the body.

Drinking hot water frequently, even when you’re not thirsty can cause an imbalance in the concentration of water in the body. Thereby causing dehydration.

Too much consumption of hot water causes an imbalance in your sleep. Avoid drinking hot water before going to bed as it would disrupt your sleep with frequent urination.

The kidney has a strong capillary system that flushes excess water and toxins out of the body. Drinking too much hot water will put pressure on the kidneys by increasing the pace at which it functions.

Since drinking hot water causes dehydration, the kidney is at risk. It would also increase the workload of the kidney, thereby leading to the overworking of this organ.

This will eventually affect your kidneys.

Frequent consumption of hot water can cause internal scalding at the linings of organs in the body system. Hot water can easily burn pr injure your lips, inner linings of the mouth and tongue.

Ensure you check the temperature of the water before drinking. It’s better consumed warm than hot.

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5 natural remedies to help you get rid of belly fat

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The tummy is a ‘problem area’ for many, and while exercise and a healthy diet are the best ways to reduce your belly fat, there are also some natural remedies that can help.

Losing fat around your tummy will also be highly beneficial to your health, since carrying weight around your stomach is a risk factor for type two diabetes, heart disease and some cancers.

Belly fat increases the risk of these life threatening conditions, because fat around your tummy is also an indicator of high levels of visceral fat (fat around your organs). Visceral fat produces more inflammatory substances than general fat (subcutaneous fat), and it is these inflammatory substances that increase the risk of developing a serious health condition.

A flat tummy is also highly desired by those who wish to highlight the curves of their hips and bum.

Ginger is not only a natural digestive aid that helps with nausea and an upset stomach, it is also thermogenic, meaning it increases your body’s temperature so that you burn fat more efficiently.

Ginger also suppresses the production of cortisol, which is a stress hormone. Stress can accelerate weight gain, so ginger can help prevent this mechanism and aid weight loss.

Drinking ginger tea daily may really help you lose belly fat.

The ingredients you need to make ginger tea are

  • 1 tablespoon of freshly grated ginger
  • 2 cups of water
  • 1 tablespoon of raw honey or pure maple syrup
  • juice from half of a lemon

Put the water in a saucepan and bring to a boil. Then add the ginger, and turn off the heat. Place the lid on the pot and let it simmer for 10 minutes.

Next, strain the tea into a mug, and then add the lemon juice and sweetener before mixing.

Using honey as your sweetener of choice, rather than refined sugar, can aid weight loss. Honey can be used in smaller quantities than refined sugar, without sacrificing sweetness, and honey also contains small traces of vitamins and minerals, which are beneficial to your overall health.

Try swapping out refined sugar in your drinks and on your cereals for example.

While drinking more water keeps you fuller longer and aids weight loss in general, there is some evidence to suggest that adding lemon can also help.

An article published by Healthline notes that the polyphenol antioxidants in lemon may both offset the negative effects of high blood glucose levels as well as reducing insulin resistance.

A simple recipe for lemon water is 2 cups of water, with the juice of half a lemon.

Squeeze the lemon into the water, grate some of the zest into the water (optional), and drink.

Polyphenols are also found in limes, so they can be a great substitute for lemons if you prefer a more gentle citrus taste. You can also try adding some turmeric. It has been shown by a study in the National Library of Medicine that the curcumin in turmeric may reduce weight gain.

Green tea contains caffeine, which has been shown to aid fat burning as well as improve performance while working out. Another factor that makes green tea beneficial to weight loss is the presence of specific catechins (a type of antioxidant), which can boost your metabolism.

Try swapping your morning tea or coffee for green tea.

Garlic, like ginger, is also thermogenic, so can also increase your body temperature to help you burn fat more efficiently.

Research in the Experimental and Therapeutic Medicine journal suggests that garlic can actually decrease body fat by increasing fat oxidation.

Adding garlic to your savoury foods is an easy way to up your intake, while you can also try the unusual combination of garlic and honey, and combine the weight loss properties of both ingredients.

What you will need is 3-4 heads of garlic, 1 cup of raw honey, and a small mason jar. Start by separating the heads of garlic into individual cloves.

Don’t peel the cloves, just remove the outer layer. Fill the jar with the unpeeled garlic cloves.

Then slowly pour the honey over the cloves. Use a spoon to make sure there aren’t any air bubbles. Make sure that all of the cloves are covered with honey, and then put the lid on.

Allow the honey to infuse for a few days in the fridge or at room temperature and take a spoonful of the combination daily on an empty stomach.

While a flat tummy might be aspirational for some, remember that overall health and contentment are the best goals to aim for. Lastly, always consume any home remedy in moderation.

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10 beauty tips you should follow during pregnancy

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Pregnancy is a time when your whole body undergoes change and your skin and hair will not stay unaffected by the hormonal roller coaster.

The clothes you wore before, will no longer fit and the beauty regime that you followed before you got pregnant might suddenly prove inadequate or ineffective.

Some pregnant women get lovely glowing skin as a result of hormonal changes while for others it might be acne time!

Staying healthy and eating right can go a long way toward making you feel beautiful during this special phase of life.

  • Stay hydrated and eat right

Make sure you drink plenty of water throughout the day to help cleanse your body of toxins. Eating plenty of fruits and vegetables is not only good for the baby, but it will also prevent your skin from looking dull and tired.

  • Acne flare-ups

If you are one of the unfortunate ones who have not been blessed with glowing skin during pregnancy, do not fret. Wash your face daily with a soap-free cleanser twice a day. Be gentle when washing and drying your skin. Do not scrub or try to squeeze the zits. Opt for oil-free moisturizers and make-up during this period.

  • Give yourself a mani-pedi

With your nails growing quicker than you can say ‘polish’, make manicures and pedicures a regular affair. Get some hand and foot scrub, some warm water and a nail file. Soak your hands and feet in warm water and shape your nails. Polish them a cheery shade and see how it lifts your spirits every morning.

  • Styling your hair

Go in for an easy maintenance haircut that you do not need to spend much time on every day. Getting hair coloured, flat ironing it or using a curler are usually considered safe after the first trimester, but just check with your doctor to be on the safe side.

  • Makeup tips

Keeping it simple works here too! If you have the pregnancy glow, then there’s nothing to worry about. However, if you have blotchy skin as a result of all those hormones, make a tube of concealer your best friend. Then brush on some pressed powder, eyeliner, and lipstick before you head out.

  • To wear or not to wear

By the time you enter your second trimester, most of your clothes will start feeling snug. That’s a great reason to get some retail therapy! Get yourself a pair of good maternity jeans or a dress, a couple of tunic tops or kurtas, and a pair of maternity leggings. You can mix and match these to get different looks every time.

  • Take care of your teeth

Pregnant women are prone to dental problems and this has been found to have an impact on the birth weight of the baby. So, make sure you practice good dental hygiene and have the perfect smile in place for your baby photos.

  • Keep moving

Strenuous exercises are a strict no-no during pregnancy, but be sure to take a short walk each day. Let the blood circulate through the body, and you’ll look much fresher! Be mobile even if you feel like you are moving in slow motion. Too much sitting or standing can lead to backaches.

  • Stretch marks

Stretch marks are inevitable be it your first pregnancy or your last. Using cocoa buttercream from the moment you find out you are expecting can, to a certain extent, help dull the marks. Massaging with castor oil or aloe vera gel has also been suggested.

  • Get adequate sleep

Last but not the least, try to sleep for a minimum of eight hours each night. Sleeping well will help keep puffy eyes at bay and prevent your skin from looking sallow. A relaxing night will keep you looking beautiful inside out.

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